| Date | Location | Result | |
| 11-27-10 | Alliance, OH | Mount Union 31, Delaware Valley 3 | Box score |
| 11-20-10 | Edwardsville, PA | Moravian 26, Wilkes 14 | Box score |
| 11-20-10 | Doylestown, PA | Delaware Valley 23, Salisbury 12 | Box score |
| 11-20-10 | Baltimore, MD | Johns Hopkins 44, Lebanon Valley 14 | Box score |
| 11-13-10 | Edwardsville, PA | Wilkes 21, King's 17 | Box score |
| 11-13-10 | Doylestown, PA | Widener 28, Delaware Valley 27 | Box score |
| 11-13-10 | Madison, NJ | Lycoming 17, FDU-Florham 10 | Box score |
| 11-13-10 | Annville, PA | Lebanon Valley 28, Albright 13 | Box score |
| 11-6-10 | Wilkes-Barre, PA | King's 45, FDU-Florham 14 | Box score |
| 11-6-10 | Chester, PA | Widener 41, Wilkes 21 | Box score |
| 11-6-10 | Williamsport, PA | Lebanon Valley 28, Lycoming 14 | Box score |
| 11-6-10 | Reading, PA | Delaware Valley 42, Albright 17 | Box score |
| 10-30-10 | Doylestown, PA | Delaware Valley 51, King's 7 | Box score |
| 10-30-10 | Annville, PA | Lebanon Valley 42, Widener 38 | Box score |
| 10-30-10 | Edwardsville, PA | Wilkes 31, Lycoming 14 | Box score |
| 10-30-10 | Madison, NJ | Albright 41, FDU-Florham 15 | Box score |
| 10-23-10 | Doylestown, PA | Delaware Valley 36, Lycoming 0 | Box score |
| 10-23-10 | Wilkes-Barre, PA | Lebanon Valley 21, King's 19 | Box score |
| 10-23-10 | Madison, NJ | Wilkes 28, FDU-Florham 23 | Box score |
| 10-23-10 | Chester, PA | Albright 35, Widener 27 | Box score |
| 10-16-10 | Edwardsville, PA | Delaware Valley 30, Wilkes 18 | Box score |
| 10-16-10 | Williamsport, PA | Lycoming 31, Widener 7 | Box score |
| 10-16-10 | Reading, PA | Albright 38, King's 14 | Box score |
| 10-16-10 | Annville, PA | Lebanon Valley 33, FDU-Florham 21 | Box score |
| 10-9-10 | Wilkes-Barre, PA | Widener 36, King's 21 | Box score |
| 10-9-10 | Madison, NJ | Delaware Valley 55, FDU-Florham 14 | Box score |
| 10-9-10 | Annville, PA | Wilkes 35, Lebanon Valley 28 | Box score |
| 10-9-10 | Reading, PA | Lycoming 50, Albright 0 | Box score |
| 10-2-10 | Chester, PA | Widener 35, FDU-Florham 20 | Box score |
| 10-2-10 | Edwardsville, PA | Wilkes 38, Albright 35 | Box score |
| 10-2-10 | Williamsport, PA | Lycoming 31, King's 24 | Box score |
| 10-2-10 | Doylestown, PA | Delaware Valley 38, Lebanon Valley 6 | Box score |
| 9-25-10 | Newport News, VA | FDU-Florham 28, Apprentice 14 | Box score |
| 9-25-10 | Utica, NY | Utica 24, Wilkes 10 | Box score |
| 9-25-10 | Williamsport, PA | Lycoming 26, Ithaca 24 | Box score |
| 9-25-10 | Reading, PA | Albright 41, Catholic 31 | Box score |
| 9-18-10 | Dover, DE | Wesley 21, Delaware Valley 17 | Box score |
| 9-18-10 | Wayne, NJ | William Paterson 14, King's 7 | Box score |
| 9-18-10 | Annville, PA | Lebanon Valley 21, Moravian 6 | Box score |
| 9-18-10 | Chester, PA | Ithaca 31, Widener 7 | Box score |
| 9-17-10 | Edwardsville, PA | Springfield 44, Wilkes 7 | Box score |
| 9-17-10 | Madison, NJ | FDU-Florham 24, Coll. of New Jersey 23 | Box score |
| 9-11-10 | Beaver Falls, PA | Albright 54, Geneva 27 | Box score |
| 9-11-10 | Doylestown, PA | Delaware Valley 27, Wash. & Jeff. 0 | Box score |
| 9-11-10 | Wilkes-Barre, PA | Bethany 31, King's 29 | Box score |
| 9-11-10 | Madison, NJ | FDU-Florham 28, St. Vincent 23 | Box score |
| 9-11-10 | Edwardsville, PA | Wilkes 38, Waynesburg 35 | Box score |
| 9-11-10 | Chester, PA | Widener 21, Thiel 0 | Box score |
| 9-11-10 | Williamsport, PA | Lycoming 40, Westminster 10 | Box score |
| 9-11-10 | Annville, PA | Grove City 17, Lebanon Valley 14 | Box score |
| 9-4-10 | Alfred, NY | Alfred 37, Widener 0 | Box score |
| 9-4-10 | Allentown, PA | Delaware Valley 27, Muhlenberg 7 | Box score |
| 9-4-10 | Glassboro, NJ | Rowan 24, Lycoming 17 | Box score |
| 9-4-10 | Reading, PA | Ursinus 21, Albright 13 | Box score |
| 9-4-10 | Annville, PA | Gettysburg 42, Lebanon Valley 28 | Box score |
| 9-3-10 | Springfield, MA | Springfield 31, King's 7 | Box score |